1. LACK OF CERTAINTY. No one knows for sure what causes multiple sclerosis (MS), a chronic disease that affects the brain, spinal cord, and optic nerves. What is known for certain is that the immune system of people with MS erodes the myelin sheath that covers and protects certain nerves, which interferes with communication between the brain and specific parts of the body. Unfortunately, no single test for diagnosing MS exists.
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